![]() In Tennessee, GoodRx is registered as a Prescription Drug Discount Plan Operator. In all states except Tennessee, GoodRx is considered a marketer of prescription discount cards. Please seek medical advice before starting, changing or terminating any medical treatment. All data provided is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders. GoodRx provides no warranty for any pricing data or other information. Age 40 to 75, 10-year ASCVD risk 7.5 (if unable to tolerate high-intensity statin) Age 40 to 75, 10-year ASCVD risk 5 to < 7.5. High Intensity Statin Therapydefined as dose expected to reduce LDL-C by greater than or equal to 50 and includes the following: (1,2) Atorvastatin 40-80mg everyday Rosuvastatin 20-40mg everyday. Question Is intensity of statin therapy associated with all-cause mortality in a large national sample of patients in the Veterans Affairs health care system with atherosclerotic cardiovascular disease. To find your exact price, please contact the pharmacy (and note that the pharmacy will need to process the information shown on your coupon to confirm the price.) The prices we show are our best estimate while we believe our data to be accurate, prices change frequently and we can’t guarantee that the price we display will exactly match the price you receive at the pharmacy. And yes, you’d better believe it includes a statin intensity chart. Most of our coupons are provided by Pharmacy Benefit Managers (PBMs), who maintain contracts with pharmacies to provide discounts. 2016 CCS Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult.GoodRx gathers prices and discounts from multiple sources, including published price lists, drug manufacturers, claims information and data provided to us by pharmacies. Table 1 Fluvastatin, 9 (1.13), 7 (1.10) Pitavastatin, 4 (0.5), 3 (0.47) Drug intensity Low-intensity statin, 171 (21.51), 214 (33.59) Moderate-intensity. Table 1: Pharmacological Treatment Indications and TargetsįRS – modified Framingham Risk Score ACR – albumin:creatinine ratio * consider LDL-C < 1.8 mmol/L for subjects with ACS within last 3 months ** statins indicated as initial therapy Cite this page contentĪnderson, Todd J. ![]() This would value more aggressive treatment in higher-risk individuals. High-intensity statin therapy was defined as atorvastatin, 40. Always use multiple peer-reviewed scholarly sources and good clinical judgement in your decision making. Moderate-intensity statin therapy was defined as atorvastatin, 10 to 20 mg, fluvastatin, 40 mg twice a day or 80 mg once a day (extended-release formulation), lovastatin, 40 mg, pitavastatin, 2 to 4 mg, pravastatin, 40 to 80 mg, rosuvastatin, 5 to 10 mg, and simvastatin, 20 to 40 mg. The author's credentials have not been confirmed. Statins reduce your body’s ability to manufacture LDL cholesterol. This might require the combination of ezetimibe (or other nonstatin medications) with maximally tolerated statin. Content on this page has not been checked for accuracy. Values and preferences: On the basis of the IMPROVE-IT trial, for those with a recent acute coronary syndrome and established coronary disease consideration should be given to more aggressive targets (LDL-C 50% reduction). The absolute risk reduction in ASCVD events associated with statin therapy can be estimated by multiplying the 10-year ASCVD risk by the anticipated relative risk reduction based on the intensity.
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